LenS3 Detector

LenS3 Multi-Angle Light Scattering Detector

The LenS3 MALS detector offers a revolutionary approach for the measurement of molecular weight (MW) and radius of gyration (Rg) of synthetic polymers, polysaccharides, proteins, and biopolymers. A novel optical design, a unique cell-block assembly, and a new calculation methodology make the LenS3 MALS detector the first groundbreaking innovation in the light scattering technology arena in decades!

Featuring a patent pending cell geometry and a lower wavelength laser (at 514 nm), the LenS3 MALS detector allows direct measurement of molecular weight and provides best-in-class sensitivity. In addition, with an improved normalization process and a new method for utilizing the angular dependence, the determination of radius of gyration of smaller macromolecules below 10 nm in gyration size, Rg, is now possible for the first time in history!

The LenS3 MALS detector is driven by SECview™ software, capable of GPC system/hardware control, multi-channel data acquisition, data processing and analysis. Totally focused around enhancing the user-interface experience, SECview is a welcoming fresh perspective that streamlines the complex calculations required by the advanced detectors and is the only GPC/SEC data processing module today that performs analysis of sample-of-interest using multiple calibration methods simultaneously.

Number of measurement angles 3
Position of the measurement angles LALS (10°)   RALS (90°)   HALS (170°)
Cell geometry proprietary conical flow path (single inlet, dual outlets)
Laser source type diode
Laser power 30 mW
Laser wavelength 514 nm
Laser temperature control yes
Wetted material teflon, PEEK, glass, stainless steel
Maximum flow rate 2 mL/min
Inlet position front or side
Baseline noise (in THF @ 1 mL/min) < 1 mV
Baseline drift (in THF @ 1 mL/min) < 1 mV / 30 min
MW range < 200 to 107 Da
 Rg> range < 2 nm to > 50 nm (in progress)
Acquisition rate < 1 to 50 Hz, user selectable
A/D board channels / resolution 8 channels / 24 bits
Dynamic range +/- 10 V
Analog inputs RI, UV and start signal
Connection to PC ethernet or USB
Dimensions 36.5 (W) × 48.5 (D) × 13 (H) mm = 1.4" × 1.9" × 0.5"
Weight 16 kg = 35 lbs
Intellectual property PCT/US19/12090: Light Scattering Detectors and Sample Cells for the Same
PCT/US19/12095: Light Scattering Detectors and Methods for the Same