Whether it is an HPLC column or a large process scale column, proper cleaning and sanitization is the single most important scheduled maintenance that will extend column lifetime. This becomes even more important if the sample applied to the column is complex or dirty.

The most popular cleaning regimens for our HPLC columns are described in the Column Rehydration and Cleaning section.

For process scale applications the Resin Sanitization section will provide valuable guidance for cleaning.

If you have particular cleaning or sanitization requirements, please contact us at techsupport.sep@tosoh.com for further recommendations.