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Toyopearl HW and TSK-GEL PW size exclusion resins are the base particles for all of Tosoh's ion exchange, hydrophobic interaction, and affinity process media.
After an initial polymerization reaction to create the designated particle size and pore size, the resin surface is chemically modified to create the desired final product.
Toyopearl HW Size Exclusion Beads
Toyopearl HW products are hydroxylated methacrylic polymer resins. Toyopearl HW beads are made commercially in many different pore sizes and particle diameters (30 micron and larger).
They vary from TSK-GEL PW beads by having a lower degree of crosslinking. Lower crosslinking makes available a larger number of resin sites for ligand immobilization when producing Toyopearl HW based ion exchange and hydrophobic interaction chromatography resins. Therefore a functionalized Toyopearl HW resin will have a higher dynamic binding capacity than the corresponding TSK-GEL PW material.
Because similarly functionalized HW and PW resin types have the same backbone polymer chemistry, the selectivity for proteins and impurities remains the same.
Toyopearl HW based resin products can be used at high linear velocities and withstand operating pressures up to
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