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Tosoh Bioscience GmbH: The Chemistry of Innovation
Process Media Products
Toyopearl Media
Process Media Products
Size Exclusion (SEC)
Ion Exchange (IEC)
Toyopearl CM-650
Toyopearl DEAE-650
Toyopearl GigaCap CM-650
Toyopearl GigaCap Family - Reduction of Elution Volume
Toyopearl GigaCap Q-650
Toyopearl GigaCap S-650
Toyopearl MegaCap II SP-550EC
Toyopearl Q-600 AR
Toyopearl QAE-550
Toyopearl SP-550
Toyopearl SP-650
Toyopearl SuperQ-650
TSKgel DEAE-5PW
TSKgel SP-3PW
TSKgel SP-5PW
TSKgel SuperQ-5PW
Hydrophobic Interaction (HIC)
Affinity (AFC)


Toyopearl SP-550 is a strong cation exchanger useful for purification of molecules such as insulin and proteins up to 100 kD. It is used for high throughput capture of feedstocks.

 Structure:





 Product Attributes:
Pore size (mean): 500 Å

Particle size (mean): 100 µm (C-grade)

Pressure rating: 3 bar

Shipping buffer: 20% ethanol

pH stability: 2-13

Shelf life: 10 years

 Literature:
Process Media Catalog - Ion Exchange Chromatography

Product Specification Sheet -
Toyopearl SP-550


Toyopearl Instruction Manual


 Comparative information for CIEX resins
Influence of pore size on Lysozyme DBC for
Toyopearl cation exchangers @ 100 cm/hour



pKa's for Ion Exchange groups

pKa's for IEX resins


Ordering information:

To place an order please contact Customer Service.

P/N Description Resin Volume Pore size

Particle size

43272 Toyopearl SP-550C 100 mL 500 Å
75 µm

14028 Toyopearl SP-550C 250 mL  500 Å 

100 µm

14705 Toyopearl SP-550C 1 L  500 Å 100 µm

14029 Toyopearl SP-550C 5 L 500 Å  100 µm

21370 ToyoScreen SP-550C 6 x 1 mL 500 Å  100 µm

21371 ToyoScreen SP-550C 6 x 5 mL 500 Å  100 µm

21394 ToyoScreen IEC Cation Mix Pack,
(GigaCap CM-650M, GigaCap S-650M, CM-650M,
SP-650M, SP-550M)
5 x 1 mL 1,000 Å  35 µm

21395 ToyoScreen IEC Cation Mix Pack,
(GigaCap CM-650M, GigaCap S-650M, CM-650M,
SP-650M, SP-550M)
5 x 5 mL 1,000 Å  35 µm

21396 ToyoScreen IEC Mix Pack,
(GigaCap CM-650M, GigaCap S-650M, GigaCap
Q-650M, Q-600C AR, SuperQ-650M, SP-550C)
6 x 1 mL 1,000 Å  35 µm

21397 ToyoScreen IEC Mix Pack, 
(GigaCap CM-650M, GigaCap S-650M, GigaCap
Q-650M, Q-600C AR, SuperQ-650M, SP-550C)
6 x 5 mL 1,000 Å

 35 µm


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NEW! Toyopearl & TSKgel
Process Media Catalog


Toyopearl Orientation Sheet

Toyopearl Brochure (en francais)

Process Media Main Page

Tosoh Bioscience GmbH Zettachring 6, 70567 Stuttgart, Germany  Tel: +49-711-132570  Email: info.tbg@tosoh.com