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Tosoh Bioscience GmbH: The Chemistry of Innovation
Process Media Products
Toyopearl Media
Process Media Products
Size Exclusion (SEC)
Ion Exchange (IEC)
Hydrophobic Interaction (HIC)
Toyopearl Butyl-600
Toyopearl Butyl-650
Toyopearl Ether-650
Toyopearl Hexyl-650
Toyopearl Phenyl-600
Toyopearl Phenyl-650
Toyopearl PPG-600
Toyopearl SuperButyl-550
TSKgel Ether-5PW
TSKgel-Phenyl-5PW
Affinity (AFC)


Toyopearl SuperButyl-550 has the second highest hydrophobicity of the HIC ligands offered by Tosoh Bioscience. Its pore size is the smallest of our three butyl resins. Primary applications are for the separation of smaller proteins. Depending on the feedstock's molecular size profile, it is also useful in negative or flow through chromatography. It can be used for capture and intermediate purification process steps.

 Structure:


Toyopearl SuperButyl chemical structure


 Hydrophobicity



Ether < PPG < Phenyl < Butyl < Hexyl
(least to most)


 Product Attributes:
Pore size (mean): 500 Å

Particle size (mean): 100 µm (C-grade)

Pressure rating: 3 bar

Shipping buffer: 20% ethanol

pH stability: 1-13

Shelf life: 10 years

 Literature:

Process Media Catalog - Hydrophobic Interaction Chromatography

Toyopearl HIC Brochure

Product Overview - Toyopearl SuperButyl-550C

Product Specification Sheet -
Toyopearl SuperButyl-550C


Toyopearl Instruction Manual


 Comparative information for HIC resins
Typical Dynamic Binding Capacities for Lysozyme

Typical Dynamic Binding Capacities for Lysozyme

Selectivities of Toyopearl HIC resins

Selectivities of Toyopearl HIC resins


Ordering information:

To place an order please contact Customer Service.

P/N Description Resin Volume Pore size

Particle size

19955 Toyopearl SuperButyl-550C 25 mL 500 Å

100 µm

19956 Toyopearl SuperButyl-550C 100 mL 500 Å

100 µm

19957 Toyopearl SuperButyl-550C 1 L 500 Å

100 µm

19958 Toyopearl SuperButyl-550C 5 L 500 Å

100 µm

21382 ToyoScreen SuperButyl-550C 6 x 1 mL  500 Å

100 µm

21383 ToyoScreen SuperButyl-550C 6 x 5 mL 500 Å

100 µm


Printer Friendly Version


NEW! Toyopearl & TSKgel
Process Media Catalog


Toyopearl Orientation Sheet

Toyopearl Brochure (en francais)

Process Media Main Page

Tosoh Bioscience GmbH Zettachring 6, 70567 Stuttgart, Germany  Tel: +49-711-132570  Email: info.tbg@tosoh.com