Toyopearl Hexyl-650

Size Exclusion (SEC)
Ion Exchange (IEC)
Hydrophobic Interaction (HIC)
	Toyopearl Butyl-600
	Toyopearl Butyl-650
	Toyopearl Ether-650
	Toyopearl Hexyl-650
	Toyopearl Phenyl-600
	Toyopearl Phenyl-650
	Toyopearl PPG-600
	Toyopearl SuperButyl-550
	TSK-GEL Ether-5PW
	TSK-GEL-Phenyl-5PW
Affinity (AFC)

Toyopearl Hexyl-650 has the highest hydrophobicity of the HIC ligands offered by Tosoh Bioscience. It is used for very hydrophilic proteins or where a low salt elution environment is required. It is useful as an early capture step or for intermediate purification.

Structure:

Hydrophobicity

Ether < PPG < Phenyl < Butyl < Hexyl
(least to most)

Product Attributes:

Pore size (mean):	1.000 Å
Particle size (mean):	100 µm (C-grade)
Pressure rating:	3 bar
Shipping buffer:	20% ethanol
pH stability:	1-13
Shelf life:	10 years

Literature:

Process Media Catalog - Hydrophobic Interaction Chromatography

Toyopearl HIC Brochure

Product Specification Sheet -
Toyopearl Hexyl-650

Toyopearl Instruction Manual

Comparative information for HIC resins

Typical Dynamic Binding Capacities for Lysozyme

Selectivities of Toyopearl HIC resins

Ordering information:
To place an order please contact Customer Service.

P/N	Description	Resin Volume	Pore size	Particle size
44465	Toyopearl Hexyl-650C	25 mL	1.000 Å	100 µm
19026	Toyopearl Hexyl-650C	100 mL	1.000 Å	100 µm
19027	Toyopearl Hexyl-650C	1 L	1.000 Å	100 µm
19028	Toyopearl Hexyl-650C	5 L	1.000 Å	100 µm
21398	ToyoScreen HIC (Ether-650M, PPG-600M, Phenyl-650M, Butyl-650M, SuperButyl-550C, Hexyl-650C)	1 mL x 6 (each)
21399	ToyoScreen HIC (Ether-650M, PPG-600M, Phenyl-650M, Butyl-650M, SuperButyl-550C, Hexyl-650C)	5 mL x 6 (each)
21378	ToyoScreen Hexyl-650C	6 x 1 mL (each)	1.000 Å	65 µm
21379	ToyoScreen Hexyl-650C	6 x 5 mL (each)	1.000 Å	65 µm

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