Toyopearl Butyl-650

Size Exclusion (SEC)
Ion Exchange (IEC)
Hydrophobic Interaction (HIC)
	Toyopearl Butyl-600
	Toyopearl Butyl-650
	Toyopearl Ether-650
	Toyopearl Hexyl-650
	Toyopearl Phenyl-600
	Toyopearl Phenyl-650
	Toyopearl PPG-600
	Toyopearl SuperButyl-550
	TSK-GEL Ether-5PW
	TSK-GEL-Phenyl-5PW
Affinity (AFC)

Toyopearl Butyl-650 has the second highest hydrophobicity of the HIC ligands offered by Tosoh Bioscience. Its pore size is the largest of our three butyl resins. Primary applications are for the separation of proteins, their isoforms, and aggregate removal. It is typically used in intermediate purification and polishing steps.

Structure:

Hydrophobicity

Ether < PPG < Phenyl < Butyl < Hexyl
(least to most)

Product Attributes:

Pore size (mean):	1.000 Å
Particle size (mean):	100µm (C-grade) 65 µm (M-grade) 35 µm (M-grade)
Pressure rating:	3 bar
Shipping buffer:	20% ethanol
pH stability:	1-13
Shelf life:	10 years

Literature:

Process Media Catalog - Hydrophobic Interaction Chromatography

Toyopearl HIC Brochure

Product Specification Sheet -
Toyopearl Butyl-650

Toyopearl Instruction Manual

Comparative information for HIC resins

Typical Dynamic Binding Capacities for Lysozyme

Selectivities of Toyopearl HIC resins

Ordering information:
To place an order please contact Customer Service.

P/N	Description	Resin Volume	Pore size	Particle size
43153	Toyopearl Butyl-650S	25 mL	1.000 Å	35 µm
07476	Toyopearl Butyl-650S	100 mL	1.000 Å	35 µm
14701	Toyopearl Butyl-650S	1 L	1.000 Å	35 µm
07975	Toyopearl Butyl-650S	5 L	1.000 Å	35 µm
19802	Toyopearl Butyl-650M	25 mL	1.000 Å	65 µm
07477	Toyopearl Butyl-650M	100 mL	1.000 Å	65 µm
14702	Toyopearl Butyl-650M	1 L	1.000 Å	65 µm
07976	Toyopearl Butyl-650M	5 L	1.000 Å	65 µm
43127	Toyopearl Butyl-650C	25 mL	1.000 Å	100 µm
07478	Toyopearl Butyl-650C	100 mL	1.000 Å	100 µm
14703	Toyopearl Butyl-650C	1 L	1.000 Å	100 µm
07977	Toyopearl Butyl-650C	5 L	1.000 Å	100 µm
21398	ToyoScreen HIC (Ether-650M, PPG-600M, Phenyl-650M, Butyl-650M, SuperButyl-550C, Hexyl-650C)	1 mL x 6 (each)
21399	ToyoScreen HIC (Ether-650M, PPG-600M, Phenyl-650M, Butyl-650M, SuperButyl-550C, Hexyl-650C)	5 mL x 6 (each)
21376	ToyoScreen Butyl-650M	1 mL x 6 (each)	1.000 Å	65 µm
21377	ToyoScreen Butyl-650M	5 mL x 6 (each)	1.000 Å	65 µm

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