The Tosoh GPC Tradition
Tosoh introduced its first line of GPC columns in 1971 and its first GPC instrument in 1972. Ever since, Tosoh scientists have made important contributions to advances in polymer analysis by Gel Permeation Chromatography. 

In 2008 at the Analytica, Munich, Tosoh Bioscience introduced the EcoSEC  GPC System, the 7th generation of dedicated GPC instruments. The EcoSEC GPC system allows faster MW determination at a lower cost per analysis. These advancements have been made possible by integrating HPLC system design with Tosoh's innovative multi-pore particle synthesis technology.

Multi-pore particle synthesis technology
Using this proprietary technology, Tosoh can manufacture particles containing a broad range of pore sizes. This innovative approach essentially creates a linear calibration curve within each particle. As a result, columns with an extended linear calibration curve can now be prepared without mixing particles of different pore sizes. 
 

Calibration curves for TSKgel SuperMultiporeHZ columns with polystyrene standards

Products First introduced in a 5 micron particle format, TSKgel MultiporeHxl-M column dimensions are 7.8 mm ID x 30 cm L for use in conventional GPC systems. Now, the innovative multi-pore technology is also available in  3, 4 and 6 micron TSKgel SuperMultiporeHZ-type columns, each featuring a distinctly different linear part of the calibration range as shown in the Figure on the right. For an overview of the innovative multipore technology, click here.