Specifically designed for purification of oligonucleotides, RNA and DNA fragments (up to 500mer), TSKgel OligoDNA RP can provide excellent separations of samples with very similar sequences.  The 250 Å pore size provides excellent kinetics for molecules with helix shape structures processing large radii of gyration. The 5 micron particle size provides a minumum of 7,000 plates per 15 centimeter column.