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Tosoh Bioscience GmbH: The Chemistry of Innovation
Reversed Phase Columns: Silica-based
TSK-GEL Columns
Reversed Phase Columns
80 Å Monomeric RP Silica
100 Å Monomeric RP Silica
Flash Intro
TSKgel ODS-100V
TSKgel ODS-100Z
2 µm Super Series RP Silica
Specialty RP Silica
High Throughput RP Silica
Protein RP Silica

TSKgel ODS-100V and TSKgel ODS-100Z columns incorporate the best-in-class surface properties to limit secondary interactions of basic, acidic and chelating compounds. Take advantage of the benefits of high column efficiency and symmetrical peak shapes to reduce your analysis and method development time!

The ultra high purity Type B base silica contains negligible amounts of metal ion impurities. Combined with monomeric bonding chemistry, this silica makes the best general purpose Reversed Phase columns suitable for the most demanding separations in quality control as well as in research and development.

 Highlights
  • Ultra-pure silica cuts down on sample adsorption
  • High surface area (450 m2/g) silica
  • Spherical 3 and 5 µm particles with 100 Å pores
  • Very high column efficiency
  • Moderate column back pressure
  • Two levels of hydrophobicity:
    • 15% carbon (100V)
    • 20% carbon (100Z)
  • Monomeric bonding chemistry
  • Low residual silanol content
    TSKgel ODS-100V TSKgel ODS-100Z
    • Lower than maximum C18 ligand density (15% C) improves wetting properties and prolongs retention of polar compounds
    • Can be used under 100% aqueous mobile phase conditions.
    • Best TSKgel column for challenging compounds, including acidic, basic, zwitterionic and chelating compounds.
  • Monomeric bonding reaction 
        followed by exhaustive
        endcapping results in:
    • High C18 ligand density (20% C)
    • Minimal silanol interaction
    • Excellent lot-to-lot reproducibility
  • Excellent general purpose  
        TSKgel column for high  
        throughput applications

  • General Principles of
    Chromatography - Mode Poster


    Reversed Phase Brochure

    Return to main Reversed Phase page
    Tosoh Bioscience GmbH Zettachring 6, 70567 Stuttgart, Germany  Tel: +49-711-132570  Email: info.tbg@tosoh.com