Highly cross-linked polymethacrylate base material of TSKgel Octadecyl-NPR provides excellent stability in high pH buffer systems and can withstand rigorous cleaning with either acid or base. 

NPR, non-porous resin, columns are prepared from non-porous methacrylate particles of uniform 2.5 micron size, which provides high efficiency separations and fast anaylses of peptides and proteins. The non-porous particle structure limits product isolation to sub-microgram loads.