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Tosoh Bioscience GmbH: The Chemistry of Innovation
Ion Exchange Chromatography
TSK-GEL Columns
HPLC Columns
Anion Exchange
Cation Exchange
TSKgel BioAssist S
TSKgel CM-2SW
TSKgel CM-3SW
TSKgel CM-5PW
TSKgel CM-STAT
TSKgel SCX
TSKgel SP-2SW
TSKgel SP-5PW
TSKgel SP-NPR
TSKgel SP-STAT


TSK-GEL CM-STAT columns are packed with 7 and 10 µm hydrophilic non-porous resin particles of which the surface consists of an open access network of multi-layered weak cation exchange groups. The innovative bonding chemistry, combined with a relatively large particle size, results in a respectable loading capacity, low operating pressure and rapid analysis.

Applications for the TSK-GEL CM-STAT columns include the separation of proteins, protein aggregates, charge isomers of monoclonal antibodies, PEGylated proteins, and peptide digests.

 Product Attributes:
Matrix: hydrophilic polymer

Particle size (mean): 7 and 10 μm

Pore size: non-porous

Functional group:

carboxymethyl
Counter ion: Na

pH range: 3.0 - 10.0

Static binding capacity (mg 
Lysozyme/mg dry gel):
ca. 20 (7 µm)
ca. 15 (10 µm)

Small ion capacity: 100 ueq/g dry gel

pKa: 4.9

 Literature:

Chromatography Catalog - Ion Exchange Chromatography

Product Overview - TSK-GEL Cation STAT
Columns


Operating Conditions and Specification -
TSK-GEL Cation Exchange STAT Columns



 Application

The analysis profiles for five antibodies on a TSKgel CM-STAT column were compared with the profiles obtained on a competitive non-porous cation exchange column. Similar or higher resolution profiles were obtained on the TSKgel CM-STAT column in approximately half the time.


TSKgel CM-STAT, 4.6 mm ID x 10 cm L




Competitor WCX-10, 4 mm ID x 25 cm L





Ordering information:

To place an order please contact
Customer Service
 
P/N Description Pore size Particle size

Dimension

21965 TSKgel CM-STAT non-porous 10 μm 3 mm ID x 3.5 cm L


21966 TSKgel CM-STAT non-porous 7 μm 4.6 mm ID x 10 cm L





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Technical support

General Principles of
Chromatography - Mode Poster


Frequently asked questions
-- IEC

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Tosoh Bioscience GmbH Zettachring 6, 70567 Stuttgart, Germany  Tel: +49-711-132570  Email: info.sep.eu@tosoh.com