The least hydrophobic of the HIC column offerings, TSKgel Butyl-NPR is the best choice for high speed separations with excellent recovery even for more hydrophobicity samples. The non-porous resin requires lower sample loading and leads to faster analysis time because the binding kinetics occur only on the bead's surface. The ultra efficient 2.5 micron bead allows for fast, high efficiency separations using a 3.5 cm L x 4.6 mm ID column format. Thus, TSKgel Butyl-NPR is ideal for time critical QC analysis or sample limited applications. Featuring polymethacrylate base material, the TSKgel Butyl-NPR column is stable in either acid or caustic cleaning regimes up to 1 N.