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Tosoh Bioscience GmbH: The Chemistry of Innovation
TSKgel® Columns
TSK-GEL Columns
Affinity Chromatography
Reversed Phase
Hydrophilic Interaction
Size Exclusion
Ion Exchange
Hydrophobic Interaction
Affinity
TSKgel Boronate-5PW
TSKgel Chelate-5PW
TSKgel Tresyl-5PW


Affinity Chromatography (AFC) offers the greatest potential specificity and selectivity for the isolation or purification of biomolecules. To enhance this advantage, three group specific ligands and one chemically active functionality are available through Tosoh Bioscience.

All analytical TSKgel AFC columns are based on the well-established 10 micron rigid TSKgel G5000PW resin. This resin features 1000 Å pores that have an estimated exclusion limit of < 10 million Da along with excellent stability from pH 2.0 to 9.0.

 



  Group Specific Ligands   Application
TSKgel Boronate-5PW Cis-diol groups found on carbohydates, glycosolyated proteins, catecholamines

TSKgel Chelate-5PW Chelates with Zn+2, Cu+2 and Ni+2 ions to target 
histidine residues on proteins

  Activated Ligands   Application
TSKgel Tresyl-5PW Reacts with amino or thiol groups, used primarily
for attachment of specific antigens for antibody
analysis



General Principles of
Chromatography - Mode Poster


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Tosoh Bioscience GmbH Zettachring 6, 70567 Stuttgart, Germany  Tel: +49-711-132570  Email: info.tbg@tosoh.com